For: Toy and Miniature Poodles
More than one form of PRA in Poodles:
The prcd gene is the cause of most but not all cases of PRA in Poodles. There appears to be at least two different genetic forms of PRA in Poodles, even though the clinical signs of PRA in all diseased dogs are very similar. One form cannot be distinguished from another form based on a clinical exam. This is significant – a dog that is Normal/Clear for prcd-PRA could still be at risk for having or carrying another form of PRA.
Predominant form of PRA in Poodles:
The exact frequency of prcd-PRA compared to other types of PRA in the Poodle is not known. We do know that prcd-PRA is frequent and is the predominant form, causing 75% or more of all PRA cases in Toy and Miniature Poodles. More information on its frequency will be gathered as more dogs are tested.
While annual eye exams by veterinary ophthalmologists are recommended for all breeds, this is especially important for Toy and Miniature Poodles since there is more than one form of PRA known to affect the breed.
Testing PRA affected Poodles:
Research on Poodles is continuing in order to identify the remaining gene(s) that cause other types of PRA. You can help if you have a Poodle that has a documented diagnosis of PRA. OptiGen will test dogs that have a CERF or a clinical exam report by a certified veterinary ophthalmologist (ACVO or ECVO diplomate or comparable) stating that PRA has been diagnosed. The owner can submit the dog’s blood sample with a copy of exam records, along with the dog’s pedigree and a statement permitting use of this dog’s blood sample for research purposes if it tests clear for prcd-PRA. There is no charge for testing PRA-affected dogs.
The Poodle Club of America Foundation (PCAF) has an agreement with the Orthopedic Foundation for Animals (OFA) to have OFA establish a database of results of the OptiGen test. Breeders who wish to list the Normal/Clear or Carrier results of their tests must submit the report they receive from OptiGen to OFA and pay a $15 fee to OFA. Their information will be entered into OFA’s DNA-based genetic database and they will receive an OFA certificate. All information in the database is publicly available. There is no charge to enter an Affected test result into the database.